TY  - JOUR
A1  - Zylka, Waldemar
A1  - Waßenberg, Jörg
T1  - Investigation of avascular tumor–immune system interactions using a CA–PDE model
T2  - Current directions in biomedical engineering
N2  - We report on investigations that illustrate the interaction between the specific immune system and a young avascular tumor growing due to a diffusive nutrient supply. We formulate a hybrid cellular automata-partial differential equation (CA-PDE) model which includes cell cycle dynamics and allows for tracking the spatial and temporal evolution of this elaborate biological system. We present results of two dimensional numerical simulations that, specifically in this work, include special cases of the spherical and papillary tumor growth, the infiltration of immune system cells into the tumor and the escape of tumor cells from the regime of the immune cells.
Y1  - 2018
UR  - https://whge.opus.hbz-nrw.de/frontdoor/index/index/docId/3155
SN  - 2364-5504
VL  - 4
IS  - 1
SP  - 615
EP  - 619
ER  -