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Design and first results of a phantom study on the suitability of iterative reconstruction for lung-cancer screening with low-dose computer tomography

  • In this research computer tomography (CT) iterative reconstruction (IR) algorithms are investigated, specifically the impact of their statistical and model-based strength on image quality in low-dose lung screening CT protocols in comparison to filtered back projection (FBP). It has been probed whether statistical, model-based IR in conjunction with low-dose, and ultra-low-dose protocols are suitable for lungcancer screening. To this end, artificial lung nodules shaped as spheres and spicules made from material with calibrated Hounsfield units (HU) were attached on marked positions in the lung structure of an anthropomorphic phantom. Nodule positions were selected by distinguished radiologists. The phantom with nodules was scanned on a CT Scanner using standard high contrast (SHC), low-dose (LD) and ultra low-dose (ULD) protocol. For reconstruction FBP and the IR algorithm ADMIRE at three different …

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Author:Britta König, Nika Guberina, Hilmar Kühl, Waldemar Zylka
Parent Title (English):Current Directions in Biomedical Engineering
Document Type:Article
Date of Publication (online):2020/01/08
Year of first Publication:2019
Publishing Institution:Westfälische Hochschule Gelsenkirchen Bocholt Recklinghausen
Release Date:2020/01/08
First Page:593
Last Page:596
Departments / faculties:Fachbereiche / Elektrotechnik und angewandte Naturwissenschaften
Licence (German):License LogoEs gilt das Urheberrechtsgesetz

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