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Background: Emotions play a central role in mental disorder and especially in depression. They are sensed in the body, and it has recently been shown in healthy participants that these sensations can be differentiated between emotions. The aim of the current study was to assess bodily sensations for basic emotions induced by emotion eliciting pictures in depression.
Methods: 30 healthy controls (HC), 30 individuals suffering from Major depressive disorder (MDD) without medication use (MDDnm) and 30 individuals with MDD with medication use (MDDm) were shown emotional and neutral pictures and were asked to paint areas in an empty body silhouette where they felt an increase or decrease in activation. Body sensation maps were then calculated and statistical pattern recognition applied.
Results Results indicated statistically separable activation patterns for all three groups. MDDnm showed less overall activation than HCs, especially in sadness and fear, while MDDm showed stronger deactivation for all emotions than the other two groups.
Conclusions: We could show that emotion experience was associated with bodily sensations that are weaker in depression than in healthy controls and that antidepressant medication was correlated with an increased feeling of bodily deactivation.
Results give insights into the relevance for clinicians to acknowledge bodily sensations in the treatment of depression.
This paper analyses the status quo of large-scale decision making combined with the possibility of blockchain as an underlying decentralized architecture to govern common pool resources in a collective manner and evaluates them according to their requirements and features (technical and non-technical). Due to an increasing trend in the distribution of knowledge and an increasing amount of information, the combination of these decentralized technologies and approaches, can not only be beneficial for consortial governance using blockchain but can also help communities to govern common goods and resources. Blockchain and its trust-enhancing properties can potenitally be a catalysator for more collaborative behavior among participants and may lead to new insights about collective action and CPRs.
A systematic method for obtaining a novel electrode structure based on PtCoMn ternary alloy catalyst supported on graphitic carbon nanofibers (CNF) for hydrogen evolution reaction (HER) in acidic media is proposed. Ternary alloy nanoparticles (Co0.6Mn0.4 Pt), with a mean crystallite diameter under 10 nm, were electrodeposited onto a graphitic support material using a two-step pulsed deposition technique. Initially, a surface functionalisation of the carbon nanofibers is performed with the aid of oxygen plasma. Subsequently, a short galvanostatic pulse electrodeposition technique is applied. It has been demonstrated that, if pulsing current is employed, compositionally controlled PtCoMn catalysts can be achieved. Variations of metal concentration ratios in the electrolyte and main deposition parameters, such as current density and pulse shape, led to electrodes with relevant catalytic activity towards HER. The samples were further characterised using several physico-chemical methods to reveal their morphology, structure, chemical and electrochemical properties. X-ray diffraction confirms the PtCoMn alloy formation on the graphitic support and energy dispersive X-ray spectroscopy highlights the presence of the three metallic components from the alloy structure. The preliminary tests regarding the electrocatalytic activity of the developed electrodes display promising results compared to commercial Pt/C catalysts. The PtCoMn/CNF electrode exhibits a decrease in hydrogen evolution overpotential of about 250 mV at 40 mA cm−2 in acidic solution (0.5 M H2SO4) when compared to similar platinum based electrodes (Pt/CNF) and a Tafel slope of around 120 mV dec−1, indicating that HER takes place under the Volmer-Heyrovsky mechanism.
Die Notwendigkeit von Nachweisen findet sich in sehr vielen Bereichen unseres Lebens. Zertifikate, Zeugnisse, Abnahmen, Rechnungen, Quittungen, Urkunden und Bescheinigungen über Fortbildungen sind nur einige Beispiele dafür. Durch die Digitalisierung, die mittlerweile so gut wie überall Einzug gehalten hat, und durch die Corona-Krise einen besonderen Schub erfahren hat, wird die Umsetzung solcher Nachweise heutzutage immer öfters digital statt auf Papier verwirklicht. Digitale Nachweise bieten viel Raum für die Optimierung von Prozessen und liefern gleichzeitig einige Schwachstellen, die zum Betrügen genutzt werden können.
Hier gilt es in der aktuellen Forschung und Entwicklung Lösungen zu finden, die die Sicherheit erhöhen, um somit die Vertrauenswürdigkeit der digitalen Nachweise zu steigern. Ob wir je komplett auf Papier verzichten werden können ist fraglich, jedoch kein unmögliches Ziel. Wer dieses Ziel verfolgt, muss nach und nach die Schwachstellen und Probleme der digitalen Nachweise ausmerzen.
2018 wurde das „DNS over HTTPS (DoH)“-Protokoll vorgestellt. Der Vorteil von DoH besteht darin, dass sich die Manipulation von DNS-Anfragen für missbräuchliche Zwecke verhindern lässt. Aus diesem Grund haben Apple, Google, Microsoft und weitere Internetfirmen DoH bereits eingebunden oder haben vor dies zu tun. Doch wie genau funktioniert die Verbesserung beim Schutz der Privatsphäre und bei der Sicherheit auf Protokollebene? Und gibt es auch Nachteile?