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IT-Risiken bei Netzwerk Videoüberwachung. Kamera-Anbieter denken bisher kaum an die Gefährdung
(2008)
Das Gesundheitswesen in Deutschland, Europa, aber auch weltweit steht gerade erst am Beginn eines notwendigen und besonderen Digitalisierungsschubs. Ein wichtiger Schritt im Rahmen dieser Digitalisierung wird es sein, sämtliche medizinische Daten leistungsträgerübergreifend einfach verfügbar zu machen. Dies ermöglicht neue Methoden der Behandlung wie durch KI-Ansätze oder die Vermeidung von Doppelbehandlungen. Zur Erreichung dieser Ziele ist es unabdingbar, dass moderne medizintechnische IT-Geräte miteinander vernetzt werden und die anfallenden Daten sicher verarbeitet und hinterlegt werden. Durch diesen Prozess entstehen aber auch neue Angriffsvektoren und die Risiken steigen erheblich an.
Diese Arbeit beschreibt zunächst grundlegende Cyber-Sicherheitsstrategien, die helfen die vorhandenen Risiken zu minimieren und mit den verbleibenden Risiken umzugehen. Zusätzlich werden konkrete Sicherheitsbedürfnisse- und Anforderungen, die zur Vernetzung von Medizintechnik und zur Verarbeitung von Daten in der Cloud, nötig sind diskutiert. Abschließend wird eine Gesamtarchitektur vorgestellt, die diese Sicherheitsbedürfnisse umsetzt.
Menschen, Technik, Götter
(2002)
Digitale Brücken nach Nepal
(2003)
Analysis of future development opportunities for OIS (Office Information Systems) methods and tools.
(1992)
Zur Wirtschaftlichkeit aktueller Technik-gestützter Geschäftsprozesse - Ein Branchenvergleich
(1995)
The number of publications describing chemical structures has increased steadily over the last decades. However, the majority of published chemical information is currently not available in machine-readable form in public databases. It remains a challenge to automate the process of information extraction in a way that requires less manual intervention - especially the mining of chemical structure depictions. As an open-source platform that leverages recent advancements in deep learning, computer vision, and natural language processing, DECIMER.ai (Deep lEarning for Chemical IMagE Recognition) strives to automatically segment, classify, and translate chemical structure depictions from the printed literature. The segmentation and classification tools are the only openly available packages of their kind, and the optical chemical structure recognition (OCSR) core application yields outstanding performance on all benchmark datasets. The source code, the trained models and the datasets developed in this work have been published under permissive licences. An instance of the DECIMER web application is available at https://decimer.ai.
The use of molecular string representations for deep learning in chemistry has been steadily increasing in recent years. The complexity of existing string representations, and the difficulty in creating meaningful tokens from them, lead to the development of new string representations for chemical structures. In this study, the translation of chemical structure depictions in the form of bitmap images to corresponding molecular string representations was examined. An analysis of the recently developed DeepSMILES and SELFIES representations in comparison with the most commonly used SMILES representation is presented where the ability to translate image features into string representations with transformer models was specifically tested. The SMILES representation exhibits the best overall performance whereas SELFIES guarantee valid chemical structures. DeepSMILES perform in between SMILES and SELFIES, InChIs are not appropriate for the learning task. All investigations were performed using publicly available datasets and the code used to train and evaluate the models has been made available to the public.
Mit Ausgabedatum Juli 2018 wurde die Norm DIN ISO 18457 "Bionik - Bionische Werkstoffe, Strukturen und Bestandteile (ISO 18457:2016) veröffentlicht. Aus diesem Anlass blicken wir auf die bisherigen Aktivitäten zurück, die zur Veröffentlichung von insgesamt drei grundlegenden Normen im Bereich der Bionik geführt haben.
When an open quantum system is driven by an external time-dependent force, the coupling of the driving to the central system is usually included, whereas the impact of the driving field on the bath is neglected. We investigate the effect of a quantum bath of linearly driven harmonic oscillators on the relaxation dynamics of a quantum two-level system which is not directly driven. In particular, we calculate the frequency-dependent response of the system when the bath is subject to Dirac and Gaussian driving pulses. We show that a time-retarded effective force on the system is induced by the driven bath which depends on the full history of the perturbation and the spectral characteristics of the underlying bath. In particular, when a structured Ohmic bath with a pronounced Lorentzian peak is considered, the dynamical response of the system to a driven bath is qualitatively different than that of the undriven bath. Specifically, additional resonances appear which can be directly associated with a Jaynes-Cummings-like effective energy spectrum.
Bestimmung der Festigkeit von pastösen Abfällen. Plädoyer für eine Novellierung der TA Abfall
(1996)
Cancer is a leading cause of morbidity and mortality worldwide, with approximately 14 million new cases and 8.2 million cancer related deaths in 2012 [1]. Moreover, the global cancer burden is expected to exceed 20 million new cancer cases by 2025. Understanding the spatial and temporal behaviour of cancer is a crucial precondition to achieve a successful treatment. Because no two cancer cases are the same, every patient should receive a treatment plan designed specifically for her case, in order to improve the patient’s survival chances.
This report gives a brief overview to the state of the art of PEM fuel cell technology and a description of a newly developed fuel cell stack concept. One main research activity at the Westphalian Energy Institute of the Westphalian University of Applied Sciences is the development of PEM fuel cells, for which a range of different materials have been investigated for fuel cell pole plate construction. Whereas graphite is a material which has suitable properties concerning conductivity as well as manufacturing e.g. for milling, stainless steel foils are suitable for economical hydroforming processes. However, with steel coating is necessary to increase corrosion resistance as well as electrical conductivity. A new fuel cell stack design is currently under development using separated single fuel cells with hydraulic cell compression. The advantages of this stack concept are modularity, effective heat exchanging and constant, uniform cell compression which are further described in this work.
This work deals with the preparation and investigation of polymer electrolyte membrane fuel cell (PEMFC) electrodes, which are obtained using gas diffusion layers coated with graphene related material (GRM) serving as a catalyst support for platinum nanoparticles. PEMFC electrocatalysts have been prepared by pulsed electrochemical deposition of platinum particles from hexachloroplatinic acid. Prior to GRM decoration with platinum, the graphene structures are functionalized by oxygen plasma treatment. This leads to oxygen containing functional groups on the GRM outer surface, providing an improved hydrophilic behavior, thus favoring the Pt deposition process. Membrane electrode assemblies (MEAs) with the so prepared electrodes are investigated in-situ in our fuel cell test system. Polarization plots (in-situ cell performance) using these MEAs have been tested under different operational conditions.
Studies on Pulse Electrodeposition of Pt-Ni binary Alloy For Electrochemical Cell Applications
(2018)
In the polymer electrolyte membrane fuel cells (PEMFC) state of the art, rare and expensive platinum group metals (PGM) or PGM alloys are used as catalyst material. Reduction of PGMs in PEMFC electrodes is strongly required to reach cost targets for this technology. An optimal catalyst utilization is achieved in case of nano-structured particles supported on carbon material with a large specific surface area. In this study, graphitic material, in form of carbon nanofibers (CNF), is decorated with Pt particles, serving as catalyst material for PEMFC electrodes with low Pt loading. As a novelty, the effect of oxygen plasma treatment of CNFs previously to platinum particle deposition has been studied. Electrodes are investigated in respect of the optimal morphology, microstructure as well as electrochemical properties. Therefore, samples are characterized by means of scanning electron microscopy combined with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetry, X-ray diffraction as well as X-ray fluorescence analysis. In order to determine the electrochemical active surface area of catalyst particles, cyclic voltammetry has been performed in 0.5 M sulphuric acid. Selected samples have been investigated in a PEMFC test bench according to their polarization behavior.
In this experimental work polymer electrolyte membrane fuel cell (PEMFC) electrodes are analysed, which are prepared by the use of two sorts of carbon nano fibres (CNF) serving as support material for platinum nano particles. Those CNFs, which are heat treated subsequently to their production, have a higher graphitisation degree than fibres as produced. The improved graphitisation degree leads to higher electrical conductivity, which is favourably for the use in PEMFC electrodes. Samples have been analysed, in order to determine graphitisation degree, electrical conductivity, as well as morphology and loading of the prepared electro catalyst. Membrane electrode assemblies manufactured from prepared electrodes are analysed in-situ in a PEM fuel cell test environment. It has been determined that power output for samples containing CNFs with higher graphitisation degree is increased by about 13.5%.
In this study, a novel design concept for PEMFC (polymer electrolytemembrane fuel cell) stacks is presented with singlecells inserted in pockets surrounded by a hydraulic medium. Thehydraulic pressure introduces necessary compression forces to themembrane electrode assembly of each cell within a stack. Moreover, homogeneous cell cooling is achieved by this medium. First,prototypes presented in this work indicate that, upscaling of cells for the novelstack design is possible without significantperformancelosses. Due to its modularity and scalability, this stackdesign meets the requirements for large PEMFC units.
The German supply chain law ( Lieferkettensorgfaltspflichtengesetz, abbreviated: LkSG) which enters into force on 1 January 2023 is part of the developing legal framework for human rights in global supply chains. Like the French vigilance law, it represents a new generation of supply chain laws which impose mandatory human rights due diligence obligations. The LkSG requires enterprises to exercise a number of due diligence obligations – from conducting risk analysis to undertaking preventive measures or remedial actions. The law is based on public enforcement via a competent authority, the Federal Office for Economic Affairs and Export Control (BAFA). The BAFA monitors and enforces compliance with the due diligence obligations. Non-compliant enterprises can be fined with up to 800,000 Euros and, in some cases, up to 2% of the annual turnover. Whilst the LkSG is an important step towards achieving greater corporate sustainability, it also has limitations. It was a political compromise and, as such, it does not include a new civil liability for non-compliance. Moreover, by default, it only applies to the enterprise’s own business area and its direct suppliers, whereas indirect suppliers are only included where the enterprise has substantiated knowledge that an obligation has been violated.
The concept of molecular scaffolds as defining core structures of organic molecules is utilised in many areas of chemistry and cheminformatics, e.g. drug design, chemical classification, or the analysis of high-throughput screening data. Here, we present Scaffold Generator, a comprehensive open library for the generation, handling, and display of molecular scaffolds, scaffold trees and networks. The new library is based on the Chemistry Development Kit (CDK) and highly customisable through multiple settings, e.g. five different structural framework definitions are available. For display of scaffold hierarchies, the open GraphStream Java library is utilised. Performance snapshots with natural products (NP) from the COCONUT (COlleCtion of Open Natural prodUcTs) database and drug molecules from DrugBank are reported. The generation of a scaffold network from more than 450,000 NP can be achieved within a single day.
Description and Analysis of Glycosidic Residues in the Largest Open Natural Products Database
(2021)
Recent experimental results showing atypical nonlinear absorption and marked deviations from well known universality in the low temperature acoustic and dielectric losses in amorphous solids prove the need for improving the understanding of the nature of two-level systems (TLSs) in these materials. Here we suggest the study of TLSs focused on their properties which are nonuniversal. Our theoretical analysis shows that the standard tunneling model and the recently suggested two-TLS model provide markedly different predictions for the experimental outcome of these studies. Our results may be directly tested in disordered lattices, e.g KBr:CN, where there is ample theoretical support for the validity of the two-TLS model, as well as in amorphous solids. Verification of our results in the latter will significantly enhance understanding of the nature of TLSs in amorphous solids, and the ability to manipulate them and reduce their destructive effect in various cutting edge applications including superconducting qubits.
Three dinuclear zinc carboxylate complexes [L1−3Zn(μ,η2-O2CPh)]2 (1, 2, 4) containing either the bidentate N,N′-chelating β-diketiminate ligand RNC(Me)C(H)C(Me)NR (R = 2,6-iPr2-C6H3, L1, complex 1), the tridentate O,N,N-chelating ligand OC(Me)C(H)C(Me)NCH2CH2NMe2 (L2, complex 2) or the bis-N,N′-chelating bis-β-diketiminate ligand RNC(Me)C(H)C(Me)NNC(Me)C(H)C(Me)NR (R = 2,6-iPr2-C6H3, L3, complex 4) were synthesized and characterized including single-crystal X-ray diffraction. Reaction of the neutral bis-β-diketimine (L3(H)2) with two equivalents of ZnMe2 leads to the expected heteroleptic dinuclear zinc complex L3(ZnMe)2 3 in 93 % yield. Further reaction with benzoic acid PhCO2H leads to complex 4. Complex 2 forms a rather strong carboxylate-bridged dimer, whereas the carboxylate groups in complexes 1 and 4 act as asymmetrical bridges between both Zn atoms, pointing to the formation of a weakly bonded dimer. The zinc atoms in 1 and 4 are tetrahedrally coordinated, whereas in 2 the coordination number is increased to five due to the coordination of the pendant donor arm. The ring opening polymerization (ROP) of rac-lactide was investigated with the zinc complexes 1–4 and diazabicycloundec-7-ene (DBU) as a co-catalyst. Complexes 2 and 3 are active polymerization catalysts, which in the presence of DBU converted 200 equiv. of rac-lactide into polylactide within 10 min at ambient temperature. The analysis of the crude polymer showed that the lactide polymerization with catalyst 2 occurs via a slightly modified activated-monomer mechanism.
Serviceangebote aus der Public Cloud schießen derzeit förmlich durch die Decke. Obwohl Coroana in einzelnen Bereichen Cloud-Projekte verzögert, gehören die Digitalisierung und damit auch Cloud Services zu den eindeutigen Gewinnersn in der Krise: Doch mit der Auslagerung von IT-Services im großen Maßstab in die Cloud, nehmen auch Cyberkriminelle dieses Umfeld mehr und mehr ins Visier. Cloud Service Provider sind zwar in der Regel sicherheitstechnisch immer auf dem neuesten Stand - aber auch sie sind angreifbar. Damit Cyberkriminelle in Cloud-Umgebungen keine Chance haben, den Blicken von Unternehemen und Strafverfolgungsbehörden zu entgehen, ist eine umfassende digitale Forensik erforderlich. In der Praxis bestehen dafür jedoch große Hürden. Deshalb müssen hier jetzt schnell neue, kreative Ansätze gefunden werden.
Damit die medizinische Versorgung weiterhin flächendeckend gewährleistet werden kann und den explodierenden Kosten Einhalt geboten wird, muss ein Gesundheitswesen der Zukunft auf digitalen Technologien basieren. Die Kritikalität der entsprechenden Health-Services ruft Cyber-Sicherheit auf den Plan – die Sensibilität der im Gesundheitswesen verarbeiteten Daten den Datenschutz. Ein zukunftsfähiges Gesundheitswesen braucht einen stringenten Rechtsrahmen, eine moderne cloudbasierte Telematikinfrastruktur, die je nach Sicherheitsbedarf in verschiedenen Modellen umgesetzt werden kann, einen restriktiven Umgang mit globalen Public-Cloud-Providern, eine besonders gesicherte, leistungsstarke Forschungsdateninfrastruktur – etwa zur Optimierung von KI-Fähigkeiten, sichere Gesundheitsanwendungen und einiges mehr. Hier ein Ausblick.
Rationale Klimaschutzpolitik
(2008)
Under ambient conditions, almost all metals are coated by an oxide. These coatings, the result of a chemical reaction, are not passive. Many of them bind, activate and modify adsorbed molecules, processes that are exploited, for example, in heterogeneous catalysis and photochemistry. Here we report an effect of general importance that governs the bonding, structure formation and dissociation of molecules on oxidic substrates. For a specific example, methanol adsorbed on the rutile TiO2(110) single crystal surface, we demonstrate by using a combination of experimental and theoretical techniques that strongly bonding adsorbates can lift surface relaxations beyond their adsorption site, which leads to a sig- nificant substrate-mediated interaction between adsorbates. The result is a complex super- structure consisting of pairs of methanol molecules and unoccupied adsorption sites. Infrared spectroscopy reveals that the paired methanol molecules remain intact and do not depro- tonate on the defect-free terraces of the rutile TiO2(110) surface.
Der Plan ist klar nachvollziehbar und notwendig: Unrechtmäßig genutzte, urheberrechtlich geschützte oder gar illegale Inhalte dürfen im Internet keine Plattform zur Verbreitung finden. Bisher geschieht das durch Analyse bereits hochgeladener Inhalte. Die Europäische Union möchte aber am liebsten verhindern, dass entsprechendes Material überhaupt ins Netz gelangt. Das ruft sogenannte Upload-Filter auf den Plan, die bereits beim Versuch des Hochladens eine Blockade setzen. So weit, so gut, jedoch lassen sich durch solche Filter zu leicht auch „unliebsame“ Inhalte blockieren – Kritikern solcher Pläne scheint ein Machtmissbrauch durch Kontrolle der zur Veröffentlichung freigegebenen Inhalte vorprogrammiert. Vor diesem Hintergrund beleuchtet folgender Beitrag den Sinn, die technische Umsetzung und Machbarkeit sowie die Risiken von Upload-Filtern.
Das Internet als weltweites Netzwerk von Servern dient schon lange nicht mehr rein der Beschaffung von Informationen oder der persönlichen Kommunikation. Es werden vermehrt mediale Inhalte (Bilder, Audio- und Videodateien) in sozialen Netzwerken gepostet. Ein Großteil dieser Inhalte dient der Selbstdarstellung des Nutzers in Chroniken, Timelines, Stories etc. Allein auf Facebook werden pro Tag etwa 350 Millionen Bilder und 100 Millionen Stunden Videomaterial von Nutzern hochgeladen. Bei YouTube sind es sogar 400 Stunden Videomaterial pro Minute.
In dieser Masse von Daten sind auch unrechtmäßig genutzte, urheberrechtlich geschützte oder illegale Inhalte vorhanden. Diese unerwünschten Inhalte können mit voller Absicht oder aus Versehen und ohne kriminellen Hintergedanken hochgeladen werden. Doch egal aus welchem Grund, solche Inhalte müssen so früh wie möglich entdeckt und gelöscht werden oder sollten gar nicht erst hochgeladen werden können. Aktuelle Lösungen basieren auf einer nachträglichen Erkennung bereits hochgeladener Inhalte durch Erkennungswerkzeuge oder den Menschen.
Dieses Vorgehen ist bereits etabliert und allseits anerkannt. Eine Erweiterung durch gesetzliche Vorgaben, die das Melden, Deaktivieren und Prüfen vereinfacht und beschleunigt, wäre hier ein logischer nächster Schritt. Doch eine Prüfung und Bewertung aller Inhalte von Uploads während des Upload-Prozesses in Echtzeit wird zurzeit favorisiert und stellt eine neue, besondere Herausforderung dar.
Daher könnten in Zukunft Upload-Filter weltweit zum Einsatz kommen. Bild 1 zeigt schematisch den Unterschied zwischen einem Upload ohne Upload-Filter – links unten – und einem Upload mit Upload-Filter – links oben. Hierbei ist die Verbindung des Upload-Filters mit dem Internet nicht obligatorisch.
Ein Upload-Filter wird als eigenständige, unumgängliche Instanz in den Upload-Prozesses integriert. Seine Aufgabe besteht in der Klassifizierung der Inhalte von Uploads.
Kriterien hierfür sind vor allem das Bestehen eines Urheberschutzes für den Upload von Musik, Bildern oder Filmen, und ein eventueller Konflikt mit dem Strafrecht – zum Beispiel Kinderpornografie oder Rassismus.
Vorangetrieben wurde das Thema von der EU – genauer durch die Richtlinie (EU) 2019/790. Der hierin enthaltene Artikel 17 sieht vor, die Plattformen zu verpflichten, Lizenzverträge mit den Inhabern von Urheberrechten zu schließen. Kommen diese nicht zustande, muss die Plattform dafür sorgen, dass entsprechende Inhalte nicht hochgeladen und veröffentlicht werden können. Dieser Artikel war und ist immer noch hoch umstritten. Die EU will damit die unerlaubte Nutzung urheberrechtlich geschützter Werke auf Webseiten verhindern.
Kritiker sehen darin das freie Internet durch eine Zensurmöglichkeit in Gefahr, sollte eine diktatorische Regierung Einfluss aufdie Upload-Filter haben.
This paper makes a contribution to the discussion on microfoundations of dynamic capabilities – actions and interactions in organizations that enable continuous organizational renewal. More specifically, we propose the idea that dynamic capabilities of an organization
are a positive function of corresponding dynamic capabilities of individual and collective actors in the organization. Further, we develop the assumption that not only individual acts of managers but also of individuals and teams without managerial responsibility relate to dynamic capabilities of the organization. Following a holistic view, we also take into consideration empowering working conditions as enhancing factor of this function. To
examine these roots of dynamic capabilities, we use a multi level model of competence provided by Wilkens, Keller and Schmette (2006) that operationalizes the concept of dynamic
capabilities provided by Teece (2007) on a concisely behavioural base. We investigated our hypotheses with a standardized questionnaire in a case study of a German plant engineering company with 112 participants and found first support for our assumptions. Our results show an impact of individual dynamic capabilities on dynamic capabilities of the organization which is mediated by team dynamic capabilities. Psychological and social-structural empowerment moderated this relationship. A case-specific interpretation and implications for future research and practice are discussed.